System Administrator, Identity & Access Management

About Us

We are developing potentially best in class therapies for patients living with severe autoimmune diseases. Our lead antibody, claseprubart (DNTH103), is purposefully engineered with extended half-life, improved potency, and high selectivity for only the active C1s complement protein that drives disease pathology – enabling less frequent and more convenient self-administered subcutaneous injections. Our second clinical candidate, DNTH212 is a first and potentially best in class, bifunctional inhibitor that targets clinically validated and complementary disease modifying mechanisms, Type 1 IFN suppression and B cell modulation – enabling potential for improved clinical outcomes and patient friendly convenient, self-administered subcutaneous injections. To learn more, please visit www.dianthustx.com and follow us on LinkedIn.

About the Role

Dianthus is growing quickly, and we are looking for a hands-on Systems Administrator with strong Identity and Access Management (IAM) expertise to help us scale securely.  You will be the operational owner of our identity platform and access governance program, responsible for “who — and what — has access to what”, covering employee, contractor, external partner (B2B), and non-human (service) identities. This is a high impact role where you will shape our identity lifecycle, strengthen our security posture, and support our SaaS and endpoint environment as we prepare for commercial scale.

We are building a culture of individuals who hold our core principles at the center of our operations, with the goal to elevate the care of our patients’ lives. We are open to you working remotely.

Key Responsibilities

Identity & Access Management

• Own the full identify lifecycle including automated provisioning/deprovisioning, and timely access revocation
• Govern external identities: Entra External ID / B2B guest access, cross-tenant collaboration, access packages, and routine guest access reviews
• Manage non-human identities: service principles, managed identities workload identities, and service accounts, including credential rotation, secret/certificate lifecycle, federated credentials
• Administer ID platform; conditional access policies, new program rollouts, identity protection, risk-based access controls, and Privileged Identity Management (PIM).
• Design and operate SSO and SCIM provisioning integrations across the SaaS application portfolio.
• Lead periodic access reviews and recertification campaigns; maintain least-privilege and role-based access control (RBAC) models across M365, Azure, and SaaS systems.
• Manage privileged access: break-glass accounts, admin role assignments, just-in-time (JIT) elevation, and segregation of duties.
• Establish and enforce external collaboration governance: which tenants can collaborate with Dianthus, what data can be shared, how guest accounts are sponsored, and how they are decommissioned.
• Support IAM audit and compliance evidence collection
• Support the response to identity-related security events in partnership with the cyber team

Endpoint, SaaS & End-User Support

• Manage the MDM/MAM environment for endpoints: configuration profiles, compliance policies, app deployment, enrollment, and remediation workflows.
• Administer the Enterprise tenant including license management, security baselines, and DLP policies.
• Provide day-to-day administration of the SaaS application portfolio, including user and license management, configuration changes, integration health monitoring, and vendor escalations.
• Deliver escalated technical support to end-users across identity, endpoint, productivity, and SaaS application issues, ensuring a high-quality employee experi…